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Myeloid leukemia with transdifferentiation plasticity developing from T‐cell progenitors

Unfavorable patient survival coincides with lineage plasticity observed in human acute leukemias. These cases are assumed to arise from hematopoietic stem cells, which have stable multipotent differentiation potential. However, here we report that plasticity in leukemia can result from instable line...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Riemke, Pia, Czeh, Melinda, Fischer, Josephine, Walter, Carolin, Ghani, Saeed, Zepper, Matthias, Agelopoulos, Konstantin, Lettermann, Stephanie, Gebhardt, Marie L, Mah, Nancy, Weilemann, Andre, Grau, Michael, Gröning, Verena, Haferlach, Torsten, Lenze, Dido, Delwel, Ruud, Prinz, Marco, Andrade‐Navarro, Miguel A, Lenz, Georg, Dugas, Martin, Müller‐Tidow, Carsten, Rosenbauer, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109237/
https://ncbi.nlm.nih.gov/pubmed/27572462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201693927
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