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Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study

A genome-wide association study (GWAS) typically is focused on detecting marginal genetic effects. However, many complex traits are likely to be the result of the interplay of genes and environmental factors. These SNPs may have a weak marginal effect and thus unlikely to be detected from a scan of...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Principais autores: Zhang, Pingye, Lewinger, Juan Pablo, Conti, David, Morrison, John L., Gauderman, W. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108681/
https://ncbi.nlm.nih.gov/pubmed/27230133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21977
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