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Sample Size Requirements to Detect Gene-Environment Interactions in Genome-wide Association Studies

Many complex diseases are likely to be a result of the interplay of genes and environmental exposures. The standard analysis in a genome-wide association study (GWAS) scans for main effects and ignores the potentially useful information in the available exposure data. Two recently proposed methods t...

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Detalhes bibliográficos
Main Authors: Murcray, Cassandra E., Lewinger, Juan Pablo, Conti, David V., Thomas, Duncan C., Gauderman, W. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076801/
https://ncbi.nlm.nih.gov/pubmed/21308767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20569
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