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Phosphorylation of the DNA-binding domain of nonhistone high-mobility group I protein by cdc2 kinase: reduction of binding affinity.

Mammalian high-mobility group I nonhistone protein (HMG-I) is a DNA-binding chromatin protein that has been demonstrated both in vitro and in vivo to be localized to the A + T-rich sequences of DNA. Recently an unusual binding domain peptide, "the A.T-hook" motif, that mediates specific interaction...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Reeves, R, Langan, T A, Nissen, M S
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1991
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1671
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