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The Saccharomyces CDC13 protein is a single-strand TG(1–3) telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

Saccharomyces telomeres consist of ≈300 bp of C(1–3)A/TG(1–3) DNA. Cells lacking the activity of the essential gene CDC13 display a cell cycle arrest mediated by the DNA damage sensing, RAD9 cell cycle checkpoint, presumably because they exhibit strand-specific loss of telomeric and telomere-adjacen...

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Detalhes bibliográficos
Main Authors: Lin, Jing-Jer, Zakian, Virginia A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19417/
https://ncbi.nlm.nih.gov/pubmed/8943008
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