The Saccharomyces CDC13 protein is a single-strand TG(1–3) telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
Saccharomyces telomeres consist of ≈300 bp of C(1–3)A/TG(1–3) DNA. Cells lacking the activity of the essential gene CDC13 display a cell cycle arrest mediated by the DNA damage sensing, RAD9 cell cycle checkpoint, presumably because they exhibit strand-specific loss of telomeric and telomere-adjacen...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13760 |
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