Transferrin receptor facilitates TGF-β and BMP signaling activation to control craniofacial morphogenesis

The Pierre Robin Sequence (PRS), consisting of cleft palate, glossoptosis and micrognathia, is a common human birth defect. However, how this abnormality occurs remains largely unknown. Here we report that neural crest cell (NCC)-specific knockout of transferrin receptor (Tfrc), a well known transfe...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Lei, R, Zhang, K, Liu, K, Shao, X, Ding, Z, Wang, F, Hong, Y, Zhu, M, Li, H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108332/
https://ncbi.nlm.nih.gov/pubmed/27362800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.170
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