NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II

Incontinentia Pigmenti (IP) is a rare X-linked disease characterized by early male lethality and multiple abnormalities in heterozygous females. IP is caused by NF-κB essential modulator (NEMO) mutations. The current mechanistic model suggests that NEMO functions as a crucial component mediating the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pescatore, Alessandra, Esposito, Elio, Draber, Peter, Walczak, Henning, Ursini, Matilde Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108330/
https://ncbi.nlm.nih.gov/pubmed/27560715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.245
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