Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus

The increased death of macrophages has been considered as a pathogenic factor for systemic lupus erythematosus (SLE), and dysfunction of autophagy may contribute to improper cell death. However, the effect of autophagy on macrophage during the pathogenesis of SLE is still unclear. Here we found that...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Li, Xiaojing, Liu, Fei, Zhang, Xuefang, Shi, Guoping, Ren, Jing, Ji, Jianjian, Ding, Liang, Fan, Hongye, Dou, Huan, Hou, Yayi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108329/
https://ncbi.nlm.nih.gov/pubmed/27537524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.244
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