Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus

The increased death of macrophages has been considered as a pathogenic factor for systemic lupus erythematosus (SLE), and dysfunction of autophagy may contribute to improper cell death. However, the effect of autophagy on macrophage during the pathogenesis of SLE is still unclear. Here we found that...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Xiaojing, Liu, Fei, Zhang, Xuefang, Shi, Guoping, Ren, Jing, Ji, Jianjian, Ding, Liang, Fan, Hongye, Dou, Huan, Hou, Yayi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108329/
https://ncbi.nlm.nih.gov/pubmed/27537524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.244
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