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Straightforward Glycoengineering Approach to Site-Specific Antibody–Pyrrolobenzodiazepine Conjugates
[Image: see text] Antibody–drug conjugates (ADCs) have become a powerful platform to deliver cytotoxic agents selectively to cancer cells. ADCs have traditionally been prepared by stochastic conjugation of a cytotoxic drug using an antibody’s native cysteine or lysine residues. Through strategic sel...
Tallennettuna:
| Julkaisussa: | ACS Med Chem Lett |
|---|---|
| Päätekijät: | , , , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Chemical
Society
2016
|
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108038/ https://ncbi.nlm.nih.gov/pubmed/27882199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00278 |
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