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Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain
Mutations in the ganglioside-induced differentiation associated protein 1 (GDAP1) cause severe peripheral motor and sensory neuropathies called Charcot-Marie-Tooth disease. GDAP1 expression induces fission of mitochondria and peroxisomes by a currently elusive mechanism, while disease causing mutati...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107993/ https://ncbi.nlm.nih.gov/pubmed/27841286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36930 |
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