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Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor

Proteins controlling mitochondrial dynamics are often targeted to and anchored into the mitochondrial outer membrane (MOM) by their carboxyl-terminal tail-anchor domain (TA). However, it is not known whether the TA modulates protein function. GDAP1 is a mitochondrial fission factor with two neighbor...

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Detalles Bibliográficos
Main Authors: Wagner, Konstanze M., Rüegg, Marcel, Niemann, Axel, Suter, Ueli
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659752/
https://ncbi.nlm.nih.gov/pubmed/19340293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005160
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