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Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves’ Disease: An Encrypted Message Sent by Animal Models

Graves’ hyperthyroidism is caused by autoantibodies directed against the thyroid-stimulating hormone receptor (TSHR) that mimic the action of TSH. The establishment of Graves’ hyperthyroidism in experimental animals has proven to be an important approach to dissect the mechanisms of self-tolerance b...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Autores principales: Luo, Yuqian, Yoshihara, Aya, Oda, Kenzaburo, Ishido, Yuko, Suzuki, Koichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107990/
https://ncbi.nlm.nih.gov/pubmed/27895620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00144
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