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Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves’ Disease: An Encrypted Message Sent by Animal Models

Graves’ hyperthyroidism is caused by autoantibodies directed against the thyroid-stimulating hormone receptor (TSHR) that mimic the action of TSH. The establishment of Graves’ hyperthyroidism in experimental animals has proven to be an important approach to dissect the mechanisms of self-tolerance b...

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Dettagli Bibliografici
Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Luo, Yuqian, Yoshihara, Aya, Oda, Kenzaburo, Ishido, Yuko, Suzuki, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107990/
https://ncbi.nlm.nih.gov/pubmed/27895620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00144
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