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Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves’ Disease: An Encrypted Message Sent by Animal Models

Graves’ hyperthyroidism is caused by autoantibodies directed against the thyroid-stimulating hormone receptor (TSHR) that mimic the action of TSH. The establishment of Graves’ hyperthyroidism in experimental animals has proven to be an important approach to dissect the mechanisms of self-tolerance b...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Luo, Yuqian, Yoshihara, Aya, Oda, Kenzaburo, Ishido, Yuko, Suzuki, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107990/
https://ncbi.nlm.nih.gov/pubmed/27895620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00144
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