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Single GDP-dissociation Inhibitor Protein regulates endocytic and secretory pathways in Leishmania

The role of GDP dissociation inhibitor (GDI) protein in regulation of Rab cycle in Leishmania is not known. Here, we have cloned and characterized the functions of GDI homologue in vivo in Leishmania. Our results have shown that LdGDI:WT along with GDP removes the Rab5 from purified endosomes and in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shanmugam, Senthil kumar, Kumar, Kamal, Singh, Pawan Kishor, Rastogi, Ruchir, Mukhopadhyay, Amitabha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107955/
https://ncbi.nlm.nih.gov/pubmed/27841328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37058
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