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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade

Mixed chimerism and tolerance can be successfully induced in rodents through allogeneic bone marrow transplantation (BMT) with costimulation blockade (CB), but varying success rates have been reported with distinct models and protocols. We therefore investigated the impact of minor antigen dispariti...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Bigenzahn, Sinda, Pree, Ines, Klaus, Christoph, Pilat, Nina, Mahr, Benedikt, Schwaiger, Elisabeth, Nierlich, Patrick, Wrba, Friedrich, Wekerle, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107841/
https://ncbi.nlm.nih.gov/pubmed/27872868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8635721
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