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Engineering Translation in Mammalian Cell Factories to Increase Protein Yield: The Unexpected Use of Long Non-Coding SINEUP RNAs
Mammalian cells are an indispensable tool for the production of recombinant proteins in contexts where function depends on post-translational modifications. Among them, Chinese Hamster Ovary (CHO) cells are the primary factories for the production of therapeutic proteins, including monoclonal antibo...
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| Publié dans: | Comput Struct Biotechnol J |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Research Network of Computational and Structural Biotechnology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107644/ https://ncbi.nlm.nih.gov/pubmed/27872686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.10.004 |
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