Identification of functional features of synthetic SINEUPs, antisense lncRNAs that specifically enhance protein translation

SINEUPs are antisense long noncoding RNAs, in which an embedded SINE B2 element UP-regulates translation of partially overlapping target sense mRNAs. SINEUPs contain two functional domains. First, the binding domain (BD) is located in the region antisense to the target, providing specific targeting...

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Publicado en:PLoS One
Autores principales: Takahashi, Hazuki, Kozhuharova, Ana, Sharma, Harshita, Hirose, Masakazu, Ohyama, Takako, Fasolo, Francesca, Yamazaki, Toshio, Cotella, Diego, Santoro, Claudio, Zucchelli, Silvia, Gustincich, Stefano, Carninci, Piero
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802440/
https://ncbi.nlm.nih.gov/pubmed/29414979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183229
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