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Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation

BACKGROUND: Mast cells are significantly involved in IgE-mediated allergic reactions; however, their roles in health and disease are incompletely understood. OBJECTIVE: We aimed to define the proteome contained in mast cell releasates upon activation to better understand the factors secreted by mast...

詳細記述

保存先:
書誌詳細
出版年:J Allergy Clin Immunol
主要な著者: Shubin, Nicholas J., Glukhova, Veronika A., Clauson, Morgan, Truong, Phuong, Abrink, Magnus, Pejler, Gunnar, White, Nathan J., Deutsch, Gail H., Reeves, Stephen R., Vaisar, Tomas, James, Richard G., Piliponsky, Adrian M.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107356/
https://ncbi.nlm.nih.gov/pubmed/27302551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.03.051
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