CRISPR interference as a titratable, trans-acting regulatory tool for metabolic engineering in the cyanobacterium Synechococcus sp. strain PCC 7002

Trans-acting regulators provide novel opportunities to study essential genes and regulate metabolic pathways. We have adapted the clustered regularly interspersed palindromic repeats (CRISPR) system from Streptococcus pyogenes to repress genes in trans in the cyanobacterium Synechococcus sp. strain...

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Publicado no:Metab Eng
Main Authors: Gordon, Gina C., Korosh, Travis C., Cameron, Jeffrey C., Markley, Andrew L., Begemann, Matthew B., Pfleger, Brian F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107151/
https://ncbi.nlm.nih.gov/pubmed/27481676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2016.07.007
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