CNS tau efflux via exosomes is likely increased in Parkinson disease but not in Alzheimer disease

BACKGROUND: Alzheimer disease (AD) and Parkinson disease (PD) involve tau pathology. Tau is detectable in blood, but its clearance from neuronal cells and the brain is poorly understood. METHODS: Tau efflux from the brain to the blood was evaluated by administering radioactively labeled and unlabele...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Alzheimers Dement
Hlavní autoři: Shi, Min, Kovac, Andrej, Korff, Ane, Cook, Travis J., Ginghina, Carmen, Bullock, Kristin M., Yang, Li, Stewart, Tessandra, Zheng, Danfeng, Aro, Patrick, Atik, Anzari, Kerr, Kathleen F., Zabetian, Cyrus P., Peskind, Elaine R., Hu, Shu-Ching, Quinn, Joseph F., Galasko, Douglas R., Montine, Thomas J., Banks, William A., Zhang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107127/
https://ncbi.nlm.nih.gov/pubmed/27234211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.04.003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky