A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents

RATIONALE: Pulmonary arterial hypertension (PAH) is a progressive and fatal disease characterized by pulmonary arterial muscularization due to excessive pulmonary vascular cell proliferation and migration, a phenotype dependent upon growth factors and activation of receptor tyrosine kinases (RTKs)....

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Tu, Ly, De Man, Frances, Girerd, Barbara, Huertas, Alice, Chaumais, Marie-Camille, Lecerf, Florence, François, Charlène, Perros, Frédéric, Dorfmüller, Peter, Fadel, Elie, Montani, David, Eddahibi, Saadia, Humbert, Marc, Guignabert, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106524/
https://ncbi.nlm.nih.gov/pubmed/22798315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201202-0309OC
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