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Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension
RATIONALE: Pulmonary vascular remodeling is key to the pathogenesis of idiopathic pulmonary arterial hypertension (IPAH). We recently reported that fibroblast growth factor-2 (FGF2) is markedly overproduced by pulmonary-endothelial cells (P-ECs) in IPAH, and contributes significantly to smooth muscl...
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| Publicat a: | Am J Respir Cell Mol Biol |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Thoracic Society
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834126/ https://ncbi.nlm.nih.gov/pubmed/21037114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0317OC |
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