Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents

Pulmonary hypertension (PH) is a progressive, lethal lung disease characterized by pulmonary artery SMC (PA-SMC) hyperplasia leading to right-sided heart failure. Molecular events originating in pulmonary ECs (P-ECs) may contribute to the PA-SMC hyperplasia in PH. Thus, we exposed cultured human PA-...

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Detalhes bibliográficos
Main Authors: Izikki, Mohamed, Guignabert, Christophe, Fadel, Elie, Humbert, Marc, Tu, Ly, Zadigue, Patricia, Dartevelle, Philippe, Simonneau, Gerald, Adnot, Serge, Maitre, Bernard, Raffestin, Bernadette, Eddahibi, Saadia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648677/
https://ncbi.nlm.nih.gov/pubmed/19197140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35070
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