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A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging
In multiple studies DNA methylation has proven to be an accurate biomarker of age. To develop these biomarkers, the methylation of multiple CpG sites is typically linearly combined to predict chronological age. By contrast, in this study we apply the Universal PaceMaker (UPM) model to investigate ch...
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| Gepubliceerd in: | PLoS Comput Biol |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106012/ https://ncbi.nlm.nih.gov/pubmed/27835646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005183 |
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