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The Epigenetic Pacemaker: modeling epigenetic states under an evolutionary framework

SUMMARY: Epigenetic rates of change, much as evolutionary mutation rate along a lineage, vary during lifetime. Accurate estimation of the epigenetic state has vast medical and biological implications. To account for these non-linear epigenetic changes with age, we recently developed a formalism insp...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Farrell, Colin, Snir, Sagi, Pellegrini, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750963/
https://ncbi.nlm.nih.gov/pubmed/32573701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa585
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