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PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases

Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorp...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Ayati, Marzieh, Koyutürk, Mehmet
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105987/
https://ncbi.nlm.nih.gov/pubmed/27835645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005195
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