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PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases

Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorp...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Ayati, Marzieh, Koyutürk, Mehmet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105987/
https://ncbi.nlm.nih.gov/pubmed/27835645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005195
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