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Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway

Follicular atresia is the main process responsible for the loss of follicles and oocytes from the ovary, and it is the root cause of ovarian aging. Apoptosis of granulosa cells (GCs) is the cellular mechanism responsible for follicular atresia in mammals. Recent advances have highlighted fundamental...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Yuan, Suzhen, Wen, Jingyi, Cheng, Jing, Shen, Wei, Zhou, Su, Yan, Wei, Shen, Lu, Luo, Aiyue, Wang, Shixuan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105915/
https://ncbi.nlm.nih.gov/pubmed/27436181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1208873
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