Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway

Follicular atresia is the main process responsible for the loss of follicles and oocytes from the ovary, and it is the root cause of ovarian aging. Apoptosis of granulosa cells (GCs) is the cellular mechanism responsible for follicular atresia in mammals. Recent advances have highlighted fundamental...

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Gepubliceerd in:Cell Cycle
Hoofdauteurs: Yuan, Suzhen, Wen, Jingyi, Cheng, Jing, Shen, Wei, Zhou, Su, Yan, Wei, Shen, Lu, Luo, Aiyue, Wang, Shixuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105915/
https://ncbi.nlm.nih.gov/pubmed/27436181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1208873
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