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Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase

Mutations that cause genome instability are considered important predisposing events that contribute to initiation and progression of cancer. Genome instability arises either due to defects in genes that cause an increased mutation rate (mutator phenotype), or defects in genes that cause chromosome...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genetics
Päätekijät: Ang, J. Sidney, Duffy, Supipi, Segovia, Romulo, Stirling, Peter C., Hieter, Philip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105872/
https://ncbi.nlm.nih.gov/pubmed/27585847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.192211
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