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Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase

Mutations that cause genome instability are considered important predisposing events that contribute to initiation and progression of cancer. Genome instability arises either due to defects in genes that cause an increased mutation rate (mutator phenotype), or defects in genes that cause chromosome...

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Bibliografski detalji
Izdano u:Genetics
Glavni autori: Ang, J. Sidney, Duffy, Supipi, Segovia, Romulo, Stirling, Peter C., Hieter, Philip
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105872/
https://ncbi.nlm.nih.gov/pubmed/27585847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.192211
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