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Mode of Action of Thiolutin, an Inhibitor of Macromolecular Synthesis in Saccharomyces cerevisiae

The sulfur-containing antibiotic thiolutin has been shown to be a potent, reversible inhibitor of the growth of Saccharomyces cerevisiae. Viability was unaffected over the concentration range of 4 to 100 μg/ml. At concentrations as low as 2 μg/ml, the drug inhibited ribonucleic acid (RNA) and protei...

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Detalhes bibliográficos
Main Authors: Jimenez, A., Tipper, D. J., Davies, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444489/
https://ncbi.nlm.nih.gov/pubmed/4597739
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