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Selection on Position of Nonsense Codons in Introns
Introns occasionally remain in mature messenger RNAs (mRNAs) due to splicing errors and the translated, aberrant proteins that result represent a metabolic cost and may have other deleterious consequences. The nonsense-mediated decay (NMD) pathway degrades aberrant mRNAs, which it recognizes by the...
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| Vydáno v: | Genetics |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5105854/ https://ncbi.nlm.nih.gov/pubmed/27630196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.189894 |
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