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Trs33-Containing TRAPP IV: A Novel Autophagy-Specific Ypt1 GEF

Ypt/Rab GTPases, key regulators of intracellular trafficking pathways, are activated by guanine-nucleotide exchange factors (GEFs). Here, we identify a novel GEF complex, TRAPP IV, which regulates Ypt1-mediated autophagy. In the yeast Saccharomyces cerevisiae, Ypt1 GTPase is required for the initiat...

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發表在:Genetics
Main Authors: Lipatova, Zhanna, Majumdar, Uddalak, Segev, Nava
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105845/
https://ncbi.nlm.nih.gov/pubmed/27672095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.194910
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