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Trs20 is required for TRAPP III complex assembly at the PAS and its function in autophagy
The modular TRAPP complex acts as a guanine-nucleotide exchange factor (GEF) for Ypt/Rab GTPases. Whereas TRAPP I and TRAPP II regulate the exocytic pathway, TRAPP III functions in autophagy. The TRAPP subunit Trs20 is not required for assembly of core TRAPP or its Ypt1 GEF activity. Interestingly,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945970/ https://ncbi.nlm.nih.gov/pubmed/24329977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12145 |
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