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A spectroscopic and calorimetric study of the melting behaviors of a "bent" and a "normal" DNA duplex: [d(GA4T4C)]2 versus [d(GT4A4C)]2.

We have calorimetrically detected and energetically characterized a premelting event in the "bent" duplex [d(GA4T4C)]2 that is absent in the "normal" duplex [d(GT4A4C)]2. This premelting may correspond to the thermally induced "unbending" of the duplex. Specifically, we have used a combination of sp...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Park, Y W, Breslauer, K J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996356/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1551
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