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In Vitro Studies Show that Sequence Variability Contributes to Marked Variation in Hepatitis B Virus Replication, Protein Expression, and Function Observed across Genotypes

The hepatitis B virus (HBV) exists as 9 major genotypes (A to I), one minor strain (designated J) and multiple subtypes. Marked differences in HBV natural history, disease progression and treatment response are exhibited by many of these genotypes and subtypes. For example, HBV genotype C is associa...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Sozzi, Vitina, Walsh, Renae, Littlejohn, Margaret, Colledge, Danni, Jackson, Kathy, Warner, Nadia, Yuen, Lilly, Locarnini, Stephen A., Revill, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105644/
https://ncbi.nlm.nih.gov/pubmed/27512071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01293-16
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