In Vitro Studies Show that Sequence Variability Contributes to Marked Variation in Hepatitis B Virus Replication, Protein Expression, and Function Observed across Genotypes

The hepatitis B virus (HBV) exists as 9 major genotypes (A to I), one minor strain (designated J) and multiple subtypes. Marked differences in HBV natural history, disease progression and treatment response are exhibited by many of these genotypes and subtypes. For example, HBV genotype C is associa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sozzi, Vitina, Walsh, Renae, Littlejohn, Margaret, Colledge, Danni, Jackson, Kathy, Warner, Nadia, Yuen, Lilly, Locarnini, Stephen A., Revill, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105644/
https://ncbi.nlm.nih.gov/pubmed/27512071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01293-16
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