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Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling
Molecular inotropy refers to cardiac contractility that can be modified to affect overall heart pump performance. Here we show evidence of a new molecular pathway for positive inotropy by a cardiac-restricted microRNA (miR). We report enhanced cardiac myocyte performance by acute titration of cardia...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5105063/ https://ncbi.nlm.nih.gov/pubmed/27833092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36803 |
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