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Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3.

During early cardiac development, the progenitor cells of the heart valves and membranous septa undergo an epithelial-mesenchymal transformation. Previous studies have shown that this transformation depends on the activity of a transforming growth factor beta (TGF beta) molecule produced by the hear...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Potts, J D, Dagle, J M, Walder, J A, Weeks, D L, Runyan, R B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1516
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