Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo

Recombinant adeno-associated virus vectors are an increasingly popular tool for gene delivery to the CNS because of their non-pathological nature, low immunogenicity, and ability to stably transduce dividing and non-dividing cells. One of the limitations of rAAVs is their preferential tropism for ne...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Schober, Alexandra L., Gagarkin, Dmitriy A., Chen, Ying, Gao, Guangping, Jacobson, Lauren, Mongin, Alexander A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104754/
https://ncbi.nlm.nih.gov/pubmed/27891076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00262
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