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General Mechanism of Two-State Protein Folding Kinetics
We describe here a general model of the kinetic mechanism of protein folding. In the Foldon Funnel Model, proteins fold in units of secondary structures, which form sequentially along the folding pathway, stabilized by tertiary interactions. The model predicts that the free energy landscape has a vo...
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| Published in: | J Am Chem Soc |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5104671/ https://ncbi.nlm.nih.gov/pubmed/25056406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5049434 |
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