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Achieving Regio- and Stereo-Control in the Fluorination of Aziridines under Acidic Conditions

We developed an efficient fluorination protocol that converts easily accessible aziridines into β-fluoroamines, which are important motifs in biologically active molecules. In contrast with traditional fluorination approaches, DMPU-HF has shown both higher reactivity and regioselectivity and good fu...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Otome, Okoromoba E., Li, Zhou, Robertson, Nicole, Mashuta, Mark M., Couto, Uenifer R., Tormena, Cláudio F., Xu, Bo, Hammond, Gerald B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104567/
https://ncbi.nlm.nih.gov/pubmed/27782265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc07855a
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