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RNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical Stress

Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent condition characterized by inflammation and progressive obstruction of the airways. At present, there is no treatment that suppresses the chronic inflammation of the disease, and COPD patients often succumb to the condition. Excessiv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schumacher, Frances-Rose, Schubert, Steffen, Hannus, Michael, Sönnichsen, Birte, Ittrich, Carina, Kreideweiss, Stefan, Kurz, Thimo, Rippmann, Jörg F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104413/
https://ncbi.nlm.nih.gov/pubmed/27832175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166352
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