Filaggrin Mutations That Confer Risk of Atopic Dermatitis Confer Greater Risk for Eczema Herpeticum

BACKGROUND: Loss-of-function null mutations R501X and 2282del4 in the skin barrier gene, filaggrin (FLG), represent the most replicated genetic risk factors for atopic dermatitis (AD). Associations have not been reported in African ancestry populations. Eczema herpeticum (ADEH) is a rare but serious...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Gao, Pei-Song, Rafaels, Nicholas M, Hand, Tracey, Murray, Tanda, Boguniewicz, Mark, Hata, Tissa, Schneider, Lynda, Hanifin, Jon M, Gallo, Richard L, Gao, Li, Beaty, Terri H, Beck, Lisa A, Barnes, Kathleen C, Leung, Donald YM
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103856/
https://ncbi.nlm.nih.gov/pubmed/19733298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.07.034
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