(5R)-5-hydroxytriptolide (LLDT-8) prevents collagen-induced arthritis through OPG/RANK/RANKL signaling in a rat model of rheumatoid arthritis

(5R)-5-hydroxytriptolide (LLDT-8) extracts from Tripterygium have anti-inflammatory, antineoplastic and immunity adjustment functions. The present study used a collagen-induced arthritis (CIA) model to evaluate whether LLDT-8 prevents collagen-induced arthritis, and investigated the signaling underl...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zeng, Ji-Zhou, Ma, Li-Feng, Meng, Hai, Yu, Hao-Miao, Zhang, Ya-Kui, Guo, Ai
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103752/
https://ncbi.nlm.nih.gov/pubmed/27882124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3739
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