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A novel KRT5 mutation associated with generalized severe epidermolysis bullosa simplex in a 2-year-old Chinese boy

Mutations in keratin 5 (KRT5) or KRT14 genes are responsible for the most severe form of epidermolysis bullosa simplex (EBS), which is EBS generalized severe (EBS-gen sev). To date, only four pathogenic mutations (p.Arg165Ser and p.Lys199Asn in KRT5; p.Arg125Cys and p.Arg125His in KRT14) have been r...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhang, Jia, Yan, Ming, Liang, Jianying, Li, Ming, Yao, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103693/
https://ncbi.nlm.nih.gov/pubmed/27882080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3717
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