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Adolescent Clinical Development of Ezogabine/Retigabine as Adjunctive Therapy for Partial-Onset Seizures: Pharmacokinetics and Tolerability

OBJECTIVES: To explore the pharmacokinetic (PK) profile and safety of ezogabine (EZG)/retigabine (RTG) as adjunctive therapy for uncontrolled partial-onset seizures (POS) in adolescents. METHODS: In this multiple-dose study (NCT01494584), adolescents with POS received EZG/RTG immediate-release table...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Tompson, Debra J., Buraglio, Mauro, Andrews, Susan M., Wheless, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103647/
https://ncbi.nlm.nih.gov/pubmed/27877093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-21.5.404
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