gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site.
Recombinantly expressed gamma-aminobutyric acid type A (GABAA) receptors consisting of alpha 1, beta 2, and gamma 2 subunits contain a binding site for benzodiazepines that differs in its properties from that of alpha 3 beta 2 gamma 2 receptors. Amino acid substitutions between the GABAA receptor al...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1421 |
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